Knowledge Base:  
Antibiotic Selection
Last Updated: 07/09/2013

Antibiotic Selection
According to Organ System

Bone  
AmikacinCiprofloxacinMarbofloxacin
AmoxicillinClindamycinMetronidazole
Amoxicillin-clavulanateEnrofloxaciTetracycline
CephalexinGentamicin 
CefazolinLincomycin 
Urinary Tract  
AmikacinCiprofloxacinTetracycline
AmoxicillinEnrofloxacinTrimethoprim-sulfa
Amoxicillin-clavulanateGentamicinTobramycin
AmpicillinMarbofloxacinVancomycin
CephalexinNitrofurantoin 
ChloramphenicolPenicillin G/V 
Prostate  
CarbenicillinClindamycinMarbofloxacin
ChloramphenicolEnrofloxacinTrimethoprim-sulfa
CiprofloxacinErythromycin 
   
Hepatic Biliary  
AminoglycosidesChloramphenicolMarbofloxacin
AmoxicillinClindamyciMetronidazole
Amoxicillin-clavulanateDoxycyclineMinocycline
AmpicillinEnrofloxacinRifampin
CephalosporinsErythromycin 
Respiratory  
AzithromycinCiprofloxacinMarbofloxacin
ChloramphenicolEnrofloxacinTrimethoprim-sulfa
Central Nervous System  
Good Penetration into CNS
ChloramphenicolMarbofloxacinTrimethoprim-sulfa
DoxycyclineMetronidazoleRifampin
EnrofloxacinMinocycline 
Intermediate to Good Penetration in CNS
CefotaximeCeftriaxonVancomycin
CeftazidimePenicillins 
Intermediate Penetration in CNS
AmoxicillinFlucytosineTicarcillin
AmpicillinKetoconazole 
Skin and Ear  
AmikacinCiprofloxacinGentamicin
Amoxicillin-ClavulanateClindamycinLincomycin
CephalexinEnrofloxacinMarbofloxacin
Cefazolin

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