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Surolan Otic Suspension, 15 ml

Surolan Otic Suspension, 15 ml
 
Sold ONLY to licensed veterinarians and pharmacies. Submit license if not already on file.
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Licensed Professional Price: $25.88
Rx:
Copy of License Required [No Prescriptions Please]
NDC: 17030-947-15
NADA: 0986-0813-15


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Product Code: 17314
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Description
 

Surolan Otic Suspension

(miconazole nitrate, polymyxin B sulfate, prednisolone acetate)

Antifungal, Antibacterial, Anti-inflammatory, Kills Ear Mites

Surolan Otic Suspension is an effective treatment for common and recurring cases of otitis externa and dermatitis in dogs. Surolan is a combination of antibiotic, antifungal and anti-inflammatory medications, including polymyxin B, miconazole and prednisolone. This formulation gives Surolan broad effectiveness against the pathogens that cause ear infections and make it less likely to develop into resistant cases. Surolan is dispensed as drops to provide a rapid, penetrating action. Additionally, it can be administered more comfortably and precisely to infected ears because it is stable and fluid at room temperature.

Surolan is used in dogs for the therapeutic treatment of otitis externa and dermatitis caused by:

  • Yeasts and fungi
    • Microsporum spp.
    • Trichophyton spp.
    • Candida spp.
    • Malassezia pachydermatis
  • Gram-positive bacteria
    • Staphylococcus spp. (sensitive strains)
    • Streptococcus spp. (sensitive strains)
  • Gram-negative bacteria
    • Pseudomona spp. (sensitive strains)
    • Escherichia coli
  • Ear mites
    • Otodectes cynotis

Surolan also has anti-inflammatory and antipruritic activity.

Dosage and Administration

Administer Surolan twice daily for seven consecutive days.

Ears: After cleaning the ear canal, apply Surolan and ensure an adequate distribution of the preparation by massaging the ear base. Apply 3-5 drops of Surolan into the ear twice daily.

Skin: Ensure the wound is well covered with Surolan and rub into the wound with a gloved hand. Apply Surolan to the affected areas twice daily.

The hair around and on lesion should be clipped at the start of treatment and again during treatment, if necessary. Surolan is non-greasy, non-staining and causes no irritation or toxic effects when applied topically.

Shake well before use.

For otic and skin use only.

Contraindications

Not to be used in animals with perforated ear-drums since polymyxin B is known to be a potential ototoxic agent. Surolan is contraindicated in dogs with suspected or known hypersensitivity to miconazole nitrate, polymyxin B sulfate or prednisolone acetate. Do not use with drugs known to induce ototoxicity.

Surolan Composition (per ml):

  • Miconazole Nitrate . . . 23 mg
  • Polymyxin B Sulphate . . . 5500 IU (= 0.696 mg)
  • Prednisolone acetate . . . 5 mg

Miconazole nitrate is a synthetic imidazole derivative with a pronounced antifungal activity and a potent activity against Gram-positive bacteria. Polymyxin B sulphate is a polypeptide antibiotic with bactericidal activity against Gram-negative bacteria. Prednisolone acetate is a glucocorticoid with strong anti-inflammatory and antipruriginous activity.

Miconazole selectively inhibits the synthesis of ergosterol, which is an essential component of the membrane of yeasts and fungi. Pollymyxin B binds to phospholipids in the cytoplasmic membrane, whereby the membrane permeability is disturbed. This results in lysis of the bacteria. The anti-inflammatory action of prednisolone acetate results from its reduction of the permeability of capillaries and vascular proliferation and from the inhibition of the fibroblast action. Membranes of the liposomes are stabilized against hypoxia, toxins etc.

  • After topical application of miconazole nitrate virtually no systemic absorption of miconazole from the skin or mucous membranes takes place.
  • Absorption of polymyxin B via the skin, mucosae, burn wounds and other wounds is negligible.
  • Systemic absorption of prednisolone on normal or abraded skin is minimal. The barrier to absorption appears to be located at the dermo-epithelial junction with longterm depot formation in the upper epidermal layers without any significant systemic absorption.

Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian

How Supplied: 15 ml and 30 ml

For Veterinary Use Only

Elanco Animal Health

Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.


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