Clomipramine HCl For Dogs
Treatment for Separation Anxiety in Dogs
Covetrus Clomipramine Hydrochloride Beef Flavored Tablets are to be used as part of a comprehensive behavioral management program to treat separation anxiety in dogs greater than 6 months of age. Inappropriate barking or destructive behavior, as well as inappropriate elimination (urination or defecation) may be alleviated by the use of Clomipramine Tablets in conjunction with behavior modification. Comparable to Virbac Clomicalm Tablets.
Separation anxiety is a complex behavior disorder displayed when the owner (or other attachment figure) leaves the dog. The signs of separation anxiety evaluated in controlled trials were vocalization, destructive behavior, excessive salivation, and inappropriate elimination. In the absence of the owner or attachment figure, dogs with separation anxiety may exhibit one or more of these clinical signs. Although the owner (attachment figure) may inadvertently misinterpret this behavior, which only happens in their absence, as spiteful, it is thought to be the result of anxiety experienced by the dog. Punishment is not considered appropriate for a dog with separation anxiety.
Proper recognition of clinical signs, including a complete patient history and assessment of the patient's household environment, is essential to accurately diagnose and treat separation anxiety.
The use of Clomipramine Tablets should not replace appropriate behavioral and environmental management but should be used to facilitate a comprehensive behavior management program.
Dosage and Administration:
The recommended daily dose of Clomipramine Tablet is 2 to 4 mg/kg/day (0.9-1.8 mg/lb/day). It can be administered as a single daily dose or divided twice daily based on patient response and/or tolerance of the side effects. It may be prudent to initiate treatment in divided doses to minimize side effects by permitting tolerance to side effects to develop or allowing the patient time to adapt if tolerance does not develop. To reduce the incidence of vomiting that may be experienced by some dogs, Clomipramine Flavored Tablets may be given with a small amount of food.
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Dog Weight (lbs)...
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Clomipramine
Per Day...
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No. Tablets per Day...
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Tablet Strength...
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2.75-5.5
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5 mg
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1
|
5 mg
|
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5.6-10.9
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10 mg
|
2
|
5 mg
|
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11-22
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20 mg
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1
|
20 mg
|
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22.1-44
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40 mg
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2
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20 mg
|
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44.1-88
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80 mg
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1
|
80 mg
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88.1-176
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160 mg
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2
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80 mg
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The specific methods of behavioral modification used in clinical trials involved desensitization and counter-conditioning techniques. Since the manifestation of separation anxiety can vary according to the individual dog, it is advised that a specific behavior modification plan be developed based on a professional assessment of each individual case.
Once the desired clinical effect is achieved and the owners have successfully instituted the appropriate behavioral modification, the dose of Clomipramine Tablets may be reduced to maintain the desired effect or discontinued. Withdrawal side effects were not reported in studies with Clomipramine Tablets in dogs. However, in clinical practice, it is recommended to taper the individual patient dose while continuing to monitor the dog's behavior and clinical status through the dose reduction or withdrawal period. Continued behavioral modification is recommended to prevent recurrence of the clinical signs.
How Supplied: Clomipramine Tablets are available in 5, 20, and 80 mg tablet strengths in color-coded packaging for oral administration to dogs. Covetrus Clomipramine is a scored tablet made with palatable beef flavoring.
Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.
