Amoxicillin
Biomox Tablets (amoxicillin) is a
broad-spectrum, semi-synthetic antibiotic which provides bactericidal
activity against a wide range of common gram-positive and gram-negative
pathogens. Amoxicillin chemically is D-(-)a-amino-p-hydroxybenzyl penicillin
trihydrate.
BIOMOX tablets are indicated in the treatment of the following
infections in dogs when caused by susceptible strains of organisms:
- Bacterial Dermatitis due to
Staphylococcus aureus, Streptococcus, Staphylococcus and
E. coli.
- Soft Tissue Infections (abscesses, wounds, lacerations) due
to Staphylococcus aureus, Streptococcus , E. coli,
Proteus mirabilis and Staphylococcus.
Amoxicillin has bactericidal
activity against susceptible organisms similar to that of ampicillin. It
acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides.
Most strains of the following gram-positive and gram-negative bacteria have
demonstrated susceptibility to amoxicillin, both in
vitro and in vivo nonpenicillinase-producing
staphylococci, alpha- and beta-hemolytic streptococci,
Streptococcus faecalis, Escherichia coli and
Proteus mirabilis. Amoxicillin does not resist destruction by
penicillinase; therefore, it is not effective against penicillinase-producing
bacteria, particularly resistant staphylococci. Most strains of
Enterobacter and Klebsiella
and all strains of Pseudomonas are resistant.
Amoxicillin may be given without regard to meals because it
is stable in gastric acid. It is rapidly absorbed following oral
administration and diffuses readily into most body fluids and tissues. It
diffuses poorly into the brain and spinal fluid except when the meninges are
inflamed. Most of amoxicillin is excreted in the urine unchanged.
Dosage and Administration:
The recommended dosage is 5 mg per pound of body weight
administered twice daily for 5 to 7 days or 48 hours after all symptoms have
subsided. If no improvement is noted in 5 days, the diagnosis should be
reconsidered and therapy changed.
Contraindications: The use of
amoxicillin is contraindicated in animals with a history of an allergic
reaction to penicillin.
Adverse Reactions:
Amoxicillin is a semisynthetic penicillin and, therefore,
has the potential for producing allergic reactions. Epinephrine and/or
steroids should be administered if an allergic reaction occurs.
For use in dogs only
Precautions:
Until adequate reproductive studies are accomplished, Biomox
(amoxicillin) tablets should not be used in pregnant or breeding animals.
Federal law restricts this drug to use by or on the order of
a licensed veterinarian
Inactive Ingredients: Dibasic Calcium
Phosphate Dihydrate, Magnesium Stearate, Microcrystalline Cellulose and
Sodium Starch Glycolate.
How Supplied:
Biomox
(amoxicillin) tablets are supplied in 50 mg, 100 mg and 200 mg
concentrations in bottles of 500 and 1000 tablets.
Store at controlled room temperature between 15° and 30°C
(59°F and 86°F)
Virbac Animal Health
