Amoxicillin For Dogs
Biomox Oral Suspension
(amoxicillin) is a
broad-spectrum, semi-synthetic antibiotic which provides bactericidal
activity against a wide range of common gram-positive and gram-negative
pathogens.
Biomox is indicated in the treatment of the
following infections in dogs when caused by susceptible strains of
organisms:
- Bacterial Dermatitis due to
Staphylococcus aureus, Streptococcus spp., Staphylococcus spp., and
E. coli.
- Soft Tissue Infections (abscesses, wounds, lacerations) due
to Staphylococcus aureus, Streptococcus, E. coli,
Proteus mirabilis and Staphylococcus.
Amoxicillin has bactericidal
activity against susceptible organisms similar to that of ampicillin. It
acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides.
Most strains of the following gram-positive and gram-negative bacteria have
demonstrated susceptibility to amoxicillin, both in
vitro and in vivo: nonpenicillinase-producing
staphylococci, alpha- and beta-hemolytic streptococci,
Streptococcus faecalis, Escherichia coli and
Proteus mirabilis. Amoxicillin does not resist destruction by
penicillinase; therefore, it is not effective against penicillinase-producing
bacteria, particularly resistant staphylococci. Most strains of
Enterobacter and Klebsiella
and all strains of Pseudomonas are resistant.
Amoxicillin may be given without regard to meals because it
is stable in gastric acid. It is rapidly absorbed following oral
administration and diffuses readily into most body fluids and tissues. It
diffuses poorly into the brain and spinal fluid except when the meninges are
inflamed. Most of amoxicillin is excreted in the urine unchanged.
Dosage and Administration: The
recommended dosage is 5 mg per pound of body weight administered twice a day
for 5 to 7 days. Continue for 48 hours after all symptoms have subsided. If
no improvement is noted within 5 days, the diagnosis should be reconsidered
and therapy changed.
Directions For Mixing Oral Suspension:
Add sufficient water to the bottle as indicated in the table below and shake
vigorously. Each mL of suspension will contain 50 mg of amoxicillin as the
trihydrate.
- 15 ml bottle - add 11 ml water
- 30 ml bottle - add 21 ml water
Contraindications: The use of
amoxicillin is contraindicated in animals with a history of an allergic
reaction to penicillin.
Adverse Reactions: Amoxicillin is a
semisynthetic penicillin and, therefore, has the potential for producing
allergic reactions. Epinephrine and/or steroids should be administered if an
allergic reaction occurs.
Inactive Ingredients: Cherry Flavor,
Silicon Dioxide NF, FD&C Red #40, Polyoxyethylene-Polyoxypropylene Glycol,
Sodium Benzoate, Sodium Citrate, Sodium Saccharin, and Sucrose.
For use in dogs only.
Precautions: Until adequate reproductive
studies are accomplished, Biomox (amoxicillin) for oral suspension should
not be used in pregnant or breeding animals.
Federal law restricts this drug
to use by or on the order of a licensed veterinarian
Note: When stored at room temperature or in refrigerator,
discard unused portion of reconstituted suspension after 14 days.
How Supplied: Biomox
(amoxicillin) for oral suspension is supplied in bottles containing 0.75 g
of amoxicillin activity in bottles of 15 mL or 1.5 g of amoxicillin activity
in bottles of 30 mL. After reconstitution with the required amount of water,
each mL will contain 50 mg of amoxicillin as the trihydrate.
SHAKE WELL BEFORE USING, KEEP TIGHTLY CLOSED
Store at controlled room temperature not to exceed 25°C (77°
F).
Virbac Animal Health
